New technology for eye diagnostics is being developed at the Wrocław University of Science and Technology

A group of scientists from Wrocław University of Science and Technology is developing a new method for functional imaging of the human retina. Their technology will be used to develop and evaluate the effectiveness of gene therapies and regenerative therapies for eye diseases, the Wrocław university announced.

A team led by Dr. Jakub Bogusławski from the Faculty of Electronics, Photonics and Microsystems at the Wrocław University of Science and Technology is working on new solutions to improve the diagnosis of eye diseases.

The project of Wrocław scientists entitled "Two-photon fluorescence lifetime ophthalmoscopy: new perspectives in the diagnosis of eye diseases" received PLN 4 million in funding from the First Team FENG FNP program, Michał Ciepielski from the Wrocław University of Science and Technology press office told PAP on Tuesday.

Dr. Bogusławski explained that two-photon fluorescence lifetime ophthalmoscopy is an advanced technique that allows for the observation of biochemical processes occurring in photoreceptor cells with high precision, without the need for sampling or tissue intervention. "This will enable the study of visual function in a completely non-invasive manner," the scientist emphasized.

Experts from Wrocław University of Science and Technology emphasize that precisely measuring fluorescence decay times in the human eye remains a technical challenge. To address this challenge, work is underway on new solutions in optics, electronics, and photonics, including femtosecond lasers and efficient systems for detecting and counting single photons, the Wrocław university emphasized in a press release.

– It is thanks to these innovations that, together with our colleagues, we will be the first in the world to apply this technology to the diagnosis of eye diseases in humans – added Dr. Bogusławski.

As emphasized, the project will be carried out at the Ultrafast Biophotonics Team, in cooperation with the International Eye Research Center in Warsaw, the University Clinical Hospital in Jena (Universitätsklinikum Jena) and InCellVu SA.

As a result, a new diagnostic tool will be created that will be used in the development and evaluation of the effectiveness of gene therapies and regenerative therapies for eye diseases.

"In the long term, our technology could contribute to the development of new therapies that will restore vision or prevent its loss. The photonic solutions we are developing represent an important step towards the development of diagnostic methods and therapies that protect visual function," added Dr. Bogusławski. (PAP)

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